Monday, October 20, 2008
Sunday, October 19, 2008
THE SO-CALLED LEGAL MEANINGS OF NATURAL PERSON, ARTIFICIAL PERSON AND SOVEREIGN PERSON
In jurisprudence, a natural person is a human being perceptible through the senses and subject to physical laws, as opposed to an artificial, legal or juristic person, i.e., an organization that the law treats for some purposes as if it were a person distinct from its members or owner.
A legal person, also called juridical person or juristic person,[1] is a legal entity through which the law allows a group of natural persons to act as if they were a single composite individual for certain purposes, or in some jurisdictions, for a single person to have a separate legal personality other than their own.[2][3] This legal fiction does not mean these entities are human beings, but rather means that the law allows them to act as persons for certain limited purposes—most commonly lawsuits, property ownership, and contracts. This concept is separate from and should not be confused with limited liability or the joint stock principle.[4] Also note that basic rights (like the rights to free speech and due process of law) do not necessarily follow from legal personhood. A legal person is sometimes called an artificial person or legal entity (although the latter is sometimes understood to include natural persons as well). Although the concept of a legal person is more central to Western law in both common law and civil law countries, it is also found in virtually every legal system.
Self-ownership (or sovereignty of the individual, individual sovereignty or individual autonomy) is the moral or natural right (aka Freedom) of a person to be the exclusive controller of his or her own body and life. It is the concept of property in one's own person. According to G. Cohen, the concept of self-ownership "says that each person enjoys, over herself and her powers, full and exclusive rights of control and use, and therefore owes no service or product to anyone else that she has not contracted to supply."
Saturday, October 18, 2008
THE REAL DRUG CARTELS
Oxycodone was first synthesized in a German laboratory in 1916, a few years after the German pharmaceutical company Bayer had stopped the mass production of heroin due to addiction and abuse by both patients and physicians. It was hoped that a thebaine-derived drug would retain the analgesic effects of morphine and heroin with less of the euphoric effect which led to addiction and over use. The subjective experience of a "high" was still reported for oxycodone, however, and it made its way into medical usage in small increments in most Western countries until the introduction of high strength preparations with inert (inactive) binders radically boosted oxycodone use. It was first introduced to the US market in May 1939 and is the active ingredient in a number of pain medications commonly prescribed for the relief of moderate to heavy pain, either with inert binders (oxycodone, OxyContin) or supplemental analgesics such as acetaminophen (Percocet, Endocet, Tylox, Roxicet) and aspirin (Percodan, Endodan, Roxiprin ). It is also sold in a sustained-release form by Mundipharma in Germany (Oxygesic), and in the United States by Purdue Pharma under the trade name OxyContin (Oxycodone Continuous release) as well as generic equivalents, and instant-release forms Endone, OxyIR, OxyNorm, Percolone, OxyFAST, Supeudol, and Roxicodone. More recently, ibuprofen has been added to oxycodone (Combunox).
The company's manufacturing takes place at three different sites, which include: Purdue Pharmaceuticals L.P., a plant located in Wilson, North Carolina; The P.F. Laboratories Inc. in Totowa, New Jersey; and Rhodes Technologies L.P. in Coventry, Rhode Island. Purdue Pharma L.P. also has research labs located in Cranbury, New Jersey. OxyContin is currently legally and illegally distributed throughout the U.S., Canada, and Mexico. Legal distribution takes place from the P.F. Laboratories Inc. in Totowa, New Jersey. An extended-release formulation of oxycodone, OxyContin, was first introduced to the US market by Purdue in 1996. Purdue has multiple patents for OxyContin.
BEFORE THERE WAS A PABLO ESCOBAR THERE WAS A ANGELO MARIANI
BEFORE THERE WAS A NICKY BARNES THERE WAS A HEINRICH DRESER:THE OWNER OF THE BRAND
Heroin was first synthesized in 1874 by C. R. Alder Wright, an English chemist working at St. Mary's Hospital Medical School in London, England. He had been experimenting with combining morphine with various acids. He boiled anhydrous morphine alkaloid with acetic anhydride over a stove for several hours and produced a more potent, acetylated form of morphine, now called diacetylmorphine. The compound was sent to F. M. Pierce of Owens College in Manchester for analysis, who reported the following to Wright:
Doses ... were subcutaneously injected into young dogs and rabbits ... with the following general results ... great prostration, fear, and sleepiness speedily following the administration, the eyes being sensitive, and pupils constrict, considerable salivation being produced in dogs, and slight tendency to vomiting in some cases, but no actual emesis. Respiration was at first quickened, but subsequently reduced, and the heart's action was diminished, and rendered irregular. Marked want of coordinating power over the muscular movements, and loss of power in the pelvis and hind limbs, together with a diminution of temperature in the rectum of about 4° (rectal failure).[7]
Wright's invention, however, did not lead to any further developments, and heroin only became popular after it was independently re-synthesized 23 years later by another chemist, Felix Hoffmann. Hoffmann, working at the Bayer pharmaceutical company in Elberfeld, Germany, was instructed by his supervisor Heinrich Dreser to acetylate morphine with the objective of producing codeine, a constituent of the opium poppy, similar to morphine pharmacologically but less potent and less addictive. But instead of producing codeine, the experiment produced an acetylated form of morphine that was actually 1.5-2 times more potent than morphine itself. Bayer would name the substance "heroin", probably from the word heroisch, German for heroic, because in field studies people using the medicine felt "heroic".[8]
From 1898 through to 1910 heroin was marketed as a non-addictive morphine substitute and cough suppressant. Bayer gave out free samples of Heroin to doctors. The doctors prescribed it to their patients. Heroin quickly gained widespread acceptance in the medical community unaware of its addictive qualities. Bayer was soon enthusiastically selling it in dozens of countries.
Something odd happened. The doctors began noticing an inordinate demand by their patients, who did not really seem to be in respiratory distress, for Heroin cough syrup. Bayer stopped producing and selling Heroin in 1913 and deleted mention of it in their official company history. Heroin was outlawed in 1924.
Inadvertently, Bayer may have caused more headaches than they have cured